淡江大學機構典藏:Item 987654321/105930
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    题名: Is End Stage Renal Disease a Risk Factor for the Mortality of Cirrhotic Patients with Esophageal Variceal Bleeding?
    作者: Hung;T. H.;Tseng;C. W.;Tseng;K. C.;Hsieh;Y. H.;Tsai;C. C.;Tsai;C. C.
    关键词: hemodialysis;portal hypertension;cirrhosis;acute renal failure;esophageal variceal bleeding
    日期: 2014-10-01
    上传时间: 2016-04-22 13:11:20 (UTC+8)
    摘要: End stage renal disease (ESRD) patients are prone to have bleeding due to uremic platelet dysfunction. However, it is still unknown if ESRD is a risk factor for the mortality of cirrhotic patients with esophageal variceal bleeding (EVB).
    METHODOLOGY:
    The National Health Insurance Database, derived from the Taiwan National Health Insurance Program, was used to enroll 6740 cirrhotic patients who were hospitalized with EVB from January 1 to December 31, 2007. The patients were matched with individuals from a national mortality database to calculate their survival time.
    RESULTS:
    Of all, 418 patients had renal function impairment (RFI) during their hospitalization. There were 209 (50%) patients with acute renal failure (ARF), and 110 (26.3%) patients with ESRD. The adjusted hazard ratios (HR) of ARF for 6-week and 1-year mortalities of cirrhotic patients with EVB were 4.90 (P<0.001) and 4.34 (P<0.001), compared to the non-RFI group. However, the adjusted HRs of ESRD for 6-week and 1-year mortalities were 1.19 (P=0.404) and 1.50 (P<0.001), compared to the non-RFI impairment group.
    CONCLUSION:
    ESRD is associated with 1-year mortality, but not a risk factor for 6-week mortality in cirrhotic patients with EVB.
    關聯: Hepato-Gastroenterology 61(135), p.1871-1875
    DOI: 10.5754/hge13666
    显示于类别:[應用數學與數據科學學系] 期刊論文

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