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    請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/105768

    題名: 不同人種及年齡對隅角開放型青光眼之視神經盤壓力影響探討
    其他題名: Study of open-angle glaucoma and the influence of pressure on the optic disc of different ethnicities and ages
    作者: 李世豪;Li, Shi-Hao
    貢獻者: 淡江大學機械與機電工程學系碩士班
    關鍵詞: 隅角開放型青光眼;人種;年齡;眼壓;視神經盤;Open-Angle Glaucoma;Ethnicities;Ages;Intraocular pressure;Optic Disc
    日期: 2015
    上傳時間: 2016-01-22 15:04:47 (UTC+8)
    摘要: 本研究針對隅角開放型青光眼的生成與發病機制建立出完整的數值模型以進行模擬及力學分析探討。隅角開放型青光眼因小樑網的病變導致房水排出受阻,使眼球前端眼壓上升在後房產生壓力堆積,後壓力經由傳遞壓迫到視神經產生視野缺損。
    In this study, the generation and pathogenesis of open-angle glaucoma is researched, and complete numerical model for simulation and mechanical analysis and discussion is established. In open-angle glaucoma, the trabecular meshwork forms lesions, causing the aqueous discharge to be blocked. The anterior chamber of the eye therefore experiences a rise in intraocular pressure in the posterior chamber, producing visual field defects due to the increased pressure on the optic disc.
    Using the finite element method simulation software ANSYS, the stress distribution inside the eyeball was found, with the stress occurring in the largest concentrations in the sclera and the optic disc at the rear of the eye.
    Variations in ethnicities of patients are investigated, specifically, the characteristic differences in the optic disc between those of Caucasian, Asian, and African descent, for the establishment of an appropriate model for simulation and analysis. It was found that, at a constant intraocular pressure and the Young''s modulus, those of African descent experienced the highest stress values, followed by Asians, with Caucasians experiencing the least of the three. This study also researches different races in conjunction with variations in the Young''s modulus and intraocular pressure under different circumstances. Internal force simulation and analyses were also discussed.
    The results of this study will allow patients to become more aware of their condition, and also provides valuable simulation data that can be referenced for related research.
    顯示於類別:[機械與機電工程學系暨研究所] 學位論文


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