English  |  正體中文  |  简体中文  |  Items with full text/Total items : 52047/87178 (60%)
Visitors : 8690685      Online Users : 76
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/105768

    Title: 不同人種及年齡對隅角開放型青光眼之視神經盤壓力影響探討
    Other Titles: Study of open-angle glaucoma and the influence of pressure on the optic disc of different ethnicities and ages
    Authors: 李世豪;Li, Shi-Hao
    Contributors: 淡江大學機械與機電工程學系碩士班
    Keywords: 隅角開放型青光眼;人種;年齡;眼壓;視神經盤;Open-Angle Glaucoma;Ethnicities;Ages;Intraocular pressure;Optic Disc
    Date: 2015
    Issue Date: 2016-01-22 15:04:47 (UTC+8)
    Abstract: 本研究針對隅角開放型青光眼的生成與發病機制建立出完整的數值模型以進行模擬及力學分析探討。隅角開放型青光眼因小樑網的病變導致房水排出受阻,使眼球前端眼壓上升在後房產生壓力堆積,後壓力經由傳遞壓迫到視神經產生視野缺損。
    In this study, the generation and pathogenesis of open-angle glaucoma is researched, and complete numerical model for simulation and mechanical analysis and discussion is established. In open-angle glaucoma, the trabecular meshwork forms lesions, causing the aqueous discharge to be blocked. The anterior chamber of the eye therefore experiences a rise in intraocular pressure in the posterior chamber, producing visual field defects due to the increased pressure on the optic disc.
    Using the finite element method simulation software ANSYS, the stress distribution inside the eyeball was found, with the stress occurring in the largest concentrations in the sclera and the optic disc at the rear of the eye.
    Variations in ethnicities of patients are investigated, specifically, the characteristic differences in the optic disc between those of Caucasian, Asian, and African descent, for the establishment of an appropriate model for simulation and analysis. It was found that, at a constant intraocular pressure and the Young''s modulus, those of African descent experienced the highest stress values, followed by Asians, with Caucasians experiencing the least of the three. This study also researches different races in conjunction with variations in the Young''s modulus and intraocular pressure under different circumstances. Internal force simulation and analyses were also discussed.
    The results of this study will allow patients to become more aware of their condition, and also provides valuable simulation data that can be referenced for related research.
    Appears in Collections:[Graduate Institute & Department of Mechanical and Electro-Mechanical Engineering] Thesis

    Files in This Item:

    File Description SizeFormat

    All items in 機構典藏 are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback