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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/105261

    Title: 含硼異腈化合物之合成及其在多組成反應上的應用
    Other Titles: Synthesis of boron-containing isocyanides and their use in isocyanide-based multicomponent reactions
    Authors: 傅嘉杰;Fu, Chia-Chieh
    Contributors: 淡江大學化學學系碩士班
    潘伯申;Pan, Po-Shen
    Keywords: 含硼異腈;多組成反應;Boron-containing;Ugi reaction;isocyanide
    Date: 2015
    Issue Date: 2016-01-22 14:51:45 (UTC+8)
    Abstract: Ugi反應合成多重含硼硼化合物(I)

    In the first project, we have developed an efficient synthesis of tris- boron-containing dipeptide derivatives using the Ugi-4CR . These compounds could be purified via acid/base extraction protocol, which provided an easy access to the boron compound libraries .

    In the second project, I have optimized the condition for the synthesis of boron-containing isocyanides Unlike the existing strategies, the described synthetic strategy offers the desire compounds with the reduced reaction time along with the simple purification protocol. . These boron-containing isocyanides were further utilized in Ugi-4CR to yield tetra-boron-containing dipeptide derivatives , in which could be used in boron neutron capture therapy .
    Appears in Collections:[化學學系暨研究所] 學位論文

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