English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 49433/84396 (59%)
造訪人次 : 7459084      線上人數 : 81
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/100078

    題名: Liquid crystal-based immunoassay for detecting human serum albumin
    作者: Chen, Chih-Hsin;Ho, Wen-Hsun
    貢獻者: 淡江大學化學學系
    日期: 2014-03-27
    上傳時間: 2015-01-28 11:05:08 (UTC+8)
    出版者: Dordrecht: Springer Netherlands
    摘要: Human serum albumin (HSA) is the most abundant protein in human blood plasma. It is commonly used as a biomarker in urine samples to identify the chronic kidney disease caused by high blood pressure or diabetes. In our research, a thin layer of liquid crystals (LCs) is used as a readout system for developing an immunoassay that reports the presence of HSA in the aqueous solution with optical signals. The detection principle of this assay is based on the variation of surface density of protein upon the specific binding of HSA on an anti-HSA immobilized surface, which leads a dark-to-bright transition of LC images under cross-polarizers. Our results show that the LC-based immunoassay can detect HSA at a concentration of 50 μg/mL. By using the slide with immobilized anti-HSA in array format, the concentration level of HSA can be simply determined by the number of LC spot shown on the slide.
    關聯: Research on Chemical Intermediates 40(6), pp.2229-2236
    DOI: 10.1007/s11164-014-1600-2
    顯示於類別:[化學學系暨研究所] 期刊論文


    檔案 大小格式瀏覽次數



    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回饋